| Hilary Swank | Amelia Earhart |
| Richard Gere | George Putnam |
| Ewan McGregor | Gene Vidal |
| Christopher Eccleston | Fred Noonan |
| Joe Anderson | Bill |
| Cherry Jones | Eleanor Roosevelt |
| Mia Wasikowska | Elinor Smith |
| Aaron Abrams | Slim Gordon |
| Dylan Roberts | Leo Bellarts |
| Scott Yaphe | William Dalten |
| Tom Fairfoot | Balfour |
| Ryann Shane | Young Amelia |
| William Cuddy | Gore Vidal |
| Elizabeth Shepherd | Frances Putnam |
| Richard Donat | Gallagher |
| Scott Anderson | Parade Reporter |
| Sarah Kitz | George's Secretary |
| Keelin Jack | Student |
| Jeremy Akerman | Sheriff |
| Derek Keurvorst | Minister |
| Thomas Hauff | Man at Opera House |
| Sarah Dood | 1st Woman at Opera |
| Danielle Bourgon | 2nd Woman at Opera |
| Hamish McEwan | Paul |
| Michael Daly | Frank Cipriani |
| Jeffrey Knight | Commander Thompson |
| Paul Johnston | Thomas O'Hare |
| Michael Richard | Reporter #1 |
| Daniel Janks | Reporter #2 |
| Ron Smerczak | Reporter #3 |
| Kerin McCue | Movie Tone Announcer |
| Richard Lothian | Coastguard Man |
| Divine Brown | Torch Singer |
| Elizabeth Saunders | Louise Thaden |
| Precious Chong | Gladys O'Donnell |
| Kathryn Haggis | Powder Puff Aviator |
| Duane Murray | Cleveland Reporter |
| Joe Renzi | Welsh Singer #1 |
| Geoff Gillespie | Welsh Singer #2 |
| Andrea Ciacci | Commodification Montage Dancer |
| Julia Juhas | Commodification Montage Dancer |
| Alexandra MacLean | Commodification Montage Dancer |
| Kristen Munro | Commodification Montage Dancer |
| Eva Redpath | Commodification Montage Dancer |
| Jamie Holmes | Commodification Montage Dancer |
| Brittany Gray | Commodification Montage Dancer |
| Karissa Strain | Commodification Montage Dancer |
| Katie Strain | Commodification Montage Dancer |
| Valerie Saija | Commodification Montage Dancer |
| Nina Strazzulla | Commodification Montage Dancer |
| James Byron | Charlie |
| Amelia Earhart | Herself (archive footage) |
| Marina Stone | Socialite |
| Leanne Melissa Bishop | Amelia's Make-up Artist (uncredited) |
